Dr Hua LINGResearch Assistant Professor


Research Assistant Professor, Department of Biochemistry, Yong Loo Lin School of Medicine, NUS
Research Cluster Lead, Wilmar-NUS Corporate Laboratory ([email protected])
Principal Investigator, NUS Synthetic Biology for Clinical and Technological Innovation (SynCTI)
Vice President, Society for Synthetic Biology (Singapore)


LING Hua received his Ph.D. in Biochemistry and Molecular Biology from Shanghai Jiao Tong University. He has made contributions to engineering microbial strains for novel functionalities such as strain tolerance, biochemical production and anti-pathogen. His research interests lie in the development of proprietary microbial strains and repurposing microbes for applications in bioproduction and human health. He received and participated in five competitive research programmes. He has published over 55 peer-reviewed articles, and his work has been presented in over 25 international conferences. He serves as a reviewer for international journals such as the Journal of Agricultural and Food Chemistry, Chemical Engineering Science, 3 Biotech, Engineering Biology, and Food and Bioproducts Processing.

Research Interest

Developing proprietary microbial strains and repurposing microbes for applications in the bioproduction and human health.

Selected Publications

  1. Ng TK, Yu AQ, Ling H, Pratomo Juwono NK, Choi WJ, Leong SSJ, Chang MW (2020) Engineering Yarrowia lipolytica towards food waste bioremediation: Production of fatty acid ethyl esters from vegetable cooking oil. Journal of Bioscience and Bioengineering. 129 (1): 31-40
  2. Xia PF, Ling H, Foo JL, Chang MW (2019) Synthetic genetic circuits for programmable biological functionalities. Biotechnology Advances. 37(6):107393
  3. Ling H, Pratomo Juwono NK, Teo WS, Liu R, Leong SSL, Chang MW (2015) Engineering transcription factors to improve tolerance against alkane biofuels in Saccharomyces cerevisiae. Biotechnology for Biofuels 2015, 8:231.
  4. Teo WS, Ling H, Yu AQ, Chang MW (2015) Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid short- and branched-chain alkyl esters biodiesel. Biotechnology for Biofuels. 2015, 8:177.
  5. Ling H, Teo W, Chen B, Leong SS, Chang MW (2014) Microbial tolerance engineering toward biochemical production: from lignocellulose to products. Current Opinion in Biotechnology. 29C:99-106.